CEDIFIX (CEFIXIME 200MG TABLET)

Cedifixim

Cefixime 200mg Dispersible Tab

INDICATIONS

  • Uncomplicated Urinary Tract Infections (E. coli and P.mirabilis)
  • Otitis Media (H. influenzae, M. catarrhalis and S. pyogenes)
  • Pharyngitis and Tonsillitis (S. pyogenes)
  • Acute Exacerbations of Chronic Bronchitis (S. pneumoniae and H. influenza)
  • Uncomplicated Gonorrhea-Cervical/Urethral (N. gonorrhoeae)

DOSAGE AND ADMINISTRATION

  • Recommended dose of Cefixime is 400 mg daily & tablet may be split and given as one half tablet every 12 hours.
  • Treatment of Uncomplicated Cervical/Urethral Gonococcal infections, a single oral dose of 400 mg is recommended.
  • Tablet may be administered without regard to food.

European Association of Urology 2011

Antimicrobial Agent Application Age Total Dose Per Day No. of Doses Per Day
Cefixime Oral 3 month 12 years 8-12mg/kg Body weight 1-2

Cleveland Clinic 2011-2012

Disease Pathogen Recommended Treatment Primary
Disseminated gonorrhea (Neisseria gonorrhoeae) Ceftriaxone 1 g IV q24h × 1-2 d or until improved, followed by cefixime 400 mg PO bid to complete total therapy of 7-10 d

NHS National Health Service 2013

Disease Adult Empirical Antimicrobial Therapy (First Choice)
Out-patient treatment of Pelvic Inflammatory Disease (PID) If patient refuses IM injection then: Cefixime PO 400mg stat then 200mg bd total 3 days & Doxycycline PO 100mg bd 14 days and Metronidazole PO 400mg bd 14 days