Tazoced
(Piperacillin & Tazobactam 2.25g /4.5g Vials)
INDICATIONS
- Intra-Abdominal Infections (Appendicitis and Peritonitis)
- Skin and Skin Structure Infections (Cellulitis, Cutaneous Abscess and Diabetic Foot Infections)
- Gynaecological Infections (Postpartum Endometritis or Pelvic Inflammatory Disease)
- Community-Acquired Lower Respiratory Tract Infections (Moderate severity only)
- Nosocomial Pneumonia (Moderate to Severe)
DOSAGE AND ADMINISTRATION
- Total daily dose for adults: 3.375 g every 6 hours.
- Should be administered by slow IV infusion over 30 minutes
DURATION OF THERAPY
- Usual duration of treatment is from 7-10 days. However, the recommended duration of therapy for treatment of Nosocomial Pneumonia is 7-14 days.
- In all conditions, the duration of therapy should be guided by the severity of the infection and the patient's clinical and bacteriological progress.
ABDOMINAL INFECTIONS | |
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Biliary tract infections (Cholecystitis and Cholangitis) - Empiric treatment for Hospital-acquired infections OR Patients with prior Biliary procedures OR Patients who are severely ill | Piperacillin/Tazobactam 3.375 g IV Q6H |
Diverticulitis - Empiric treatment for Severe infections | |
Secondary peritonitis/Gl perforation - Empiric treatment for Patient Severely ill or Imunosuppressed |
PULMONARY INFECTIONS | |
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Community-acquired Pneumonia in hospitalized patients-Empiric treatment when patient in the ICU; At risk for infection with Pseudomonas | Piperacillin/Tazobactam 4.5 g IV Q6H PLUS Azithromycin 500 mg IV Q24H |
Healthcare-acquired Pneumonia (NOT ventilator-associated) Empiric treatment for Patient with Severe illness (e.g., in or transferring to the ICU/intermediate care unit, concern for sepsis, significant oxygen requirement, multi-lobar consolidation) | Piperacillin/tazobactam 4.5 g IV Q6H Vancomycin |
Ventilator-associated pneumonia (VAP) Empiric treatment for Late-onset VAP; All VAP that is not early-onset | Vancomycin PLUS [Piperacillin/ Tazobactam 4.5 g IV Q6H OR Cefepime 2 g IV OR Q8H] Tobramycin |